Postdoctoral Fellow – Indiana Center for Regenerative Medicine and Engineering (Nanofabrication)

Indiana University at Bloomington

Description

This is a grant funded opportunity with a specific focus on performing Investigations on the development of the microneedle-based drug delivery method using computational simulation to understand the drug delivery mechanism and optimize the design of the microneedles. Research on the design of the nanodevices toward the optical sensing of the biomolecules with high sensitivity working with the Indiana Center for Regenerative Medicine and Engineering.

The Laboratory of Dr. Yi Xuan in Department of Surgery and the Indiana Center for Regenerative Medicine and Engineering at Indiana University School of Medicine is seeking a highly motivated postdoctoral fellow to work on projects addressing the mechanisms of gene delivery and transfection. This opportunity will work with group members to develop multiphysics model to simulate the gene delivery process by using the microneedle-based chip subject to the applied electric field. Based on the established relation between drug delivery process and structure of microneedle, this opportunity will design and optimize the microneedles. Contributes to overall project management and cross functional working groups to facilitate development and finalization of the microneedle-based chip for drug delivery.

To learn more about the Indiana Center for Regenerative Medicine and Engineering please follow this link: https: // medicine.iu.edu/research/centers- institutes/regenerative-medicine-and-engineering/

IU School of Medicine is committed to providing inclusive benefits for eligible employees and their families. Please click here to learn more: https: // hr.iu.edu/benefits/#loaded

As the nation's largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.

Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the largest concentrations of health sciences companies in the nation. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life – the city possesses a variety of professional sports, arts venues and outdoor recreation areas. Residents of this dynamic city, and surrounding suburbs, enjoy leading educational systems and top-ranked universities, paired with a diverse population. Indianapolis International Airport is a top-ranked international airport, being named “Best Airport in North America” by Airports Council International for many years. For additional information on life in Indy: https: // faculty.medicine.iu.edu/relocation/.

Basic Qualifications

Collaborates with group members to design nanophotonics for biosensing. Optimizes the structure of nanodevices toward the optical sensing application, after which fabrication is needed to obtain the designed devices for later experiments. Conducts experiments to examine the sensitivity of the fabricated devices for sensing the target biomolecules.

Minimum Education: A PhD degree in Physics, Electric Engineering, Mechanical Engineering, or Biomedical Engineering.

Minimum Experience:

  Familiar with numerical simulation of electrophoresis and electroporation.

  Experience with simulation and testing for optical nanodevices such as microring resonators.

  Background with basic electromagnetics to model the optical sensing phenomena.

  Excellent writing skills and oral communication skills.

  Experience in multiphysics computational simulation with finite element method, familiar with commercial software, such as COMSOL.

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