招聘簡(jiǎn)介：

　　·辛辛那提兒童醫(yī)院醫(yī)療中心

　　·地點(diǎn)：俄亥俄州辛辛那提

　　·工作編號(hào)：7056467（參考號(hào)：105097）

　　·發(fā)布日期：2019年3月14日

　　·申請(qǐng)截止日期：開(kāi)放至填寫(xiě)

　　職位描述

　　Timchenko實(shí)驗(yàn)室正在尋找一名博士后研究員來(lái)研究肌強(qiáng)直性營(yíng)養(yǎng)不良1型（DM1）的機(jī)制和治療方法。實(shí)驗(yàn)室主要研究成人和先天性DM1的轉(zhuǎn)化研究。我們利用人類組織樣本、人類原代培養(yǎng)細(xì)胞和小鼠模型對(duì)DM1和CDM1進(jìn)行檢測(cè)，以探討GSK3信號(hào)在DM1分子病理生理學(xué)中的作用。PostDoc將調(diào)查CDM1和DM1中的GSK3目標(biāo)。

　　要求：具有鼠類疾病模型、細(xì)胞培養(yǎng)和分子研究的博士學(xué)位者優(yōu)先。

　　英文原文：

　　·         Cincinnati Children's Hospital Medical Center

　　·         Location: Cincinnati, OH

　　·         Job Number: 7056467 (Ref #: 105097)

　　·         Posting Date: Mar 14, 2019

　　·         Application Deadline: Open Until Filled

　　Job Description

　　The Timchenko Laboratory is seeking a post-doctoral fellow to investigate mechanisms and treatments of Myotonic Dystrophy type 1 (DM1). The laboratory is focused on translational studies of adult and congenital DM1. We use human tissue samples, human primary cultured cells and mouse models for DM1 and CDM1 to examine the role of GSK3 signaling in DM1 molecular pathophysiology. The postdoc will investigate GSK3 targets in CDM1 and DM1.

　　Requirements: Candidates with PhD degree with experience in murine models of disease, cell culture and molecular studies are preferred.

　　Please submit your applications to Dr. Timchenko (Lubov.Timchenko@cchmc.org) with the following information: cover letter, CV and contact information for 3 referees.

　　Cincinnati Children’s Research Foundation

　　Cincinnati Children’s Hospital Medical Center (CCHMC) is a premier pediatric research institution with over 900 diverse and productive faculty members. Here, researchers work collaboratively across specialties and divisions to address some of the biggest challenges we face today in improving child health. A strong network of research support services and facilities, along with institutional commitment to research, push our team of faculty, postdocs and support staff to explore the boundaries of what is possible, leading to significant breakthroughs. We are driven by our mission to improve child health and transform the delivery of care through fully integrated, globally recognized research, education and innovation.

　　Post-doctoral Research Fellows at Cincinnati Children’s are valued for their unique interests and strengths, and are supported by our institution’s strong programming for post-docs through the Office of Postdoctoral Affairs and the Office of Academic Affairs and Career Development. Cincinnati Children’s is a respected part of the broader, and very vibrant, Cincinnati community. With a thriving arts scene, numerous festivals celebrating music and food, a passionate fan following for our college and professional sports teams, and a variety of opportunities for outdoor activities, our region is truly a great place to work and live.

　　For further information about working at CCHMC, please contact the Postdoc recruiter: Michael Bennett, Ph.D. – research@cchmc.org

　　To apply online go to: https://jobs.cincinnatichildrens.org/search/searchjobs and search for job (requisition) number 105097.

　　Cincinnati Children’s Hospital Medical Center is an Affirmative Action/Equal Opportunity Institution

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