美國希望之城2023年招聘博士后職位（女性癌癥發病機制和治療）

希望之城國家醫療中心(City of Hope NationalMedical Center)是一所頂尖的美國非盈利研究和治療中心，專注于癌癥、糖尿病和其他危及生命的疾病。

Postdoctoral Fellow - Womens Cancer Pathogenesis and Therapeutics

City of Hope

Job Description

About City of Hope

City of Hope's mission is to deliver the cures of tomorrow to the people who need them today. Founded in 1913,City of Hopehas grown into one of the largest cancer research and treatment organizations in the U.S. and one of the leading research centers for diabetes and other life-threatening illnesses. City of Hope research has been the basis fornumerous breakthrough cancer medicines, as well as human synthetic insulin and monoclonal antibodies. With an independent, National Cancer Institute-designated comprehensive cancer center at its core, City of Hope brings a uniquely integrated model to patients spanning cancer care, research and development, academics and training, and innovation initiatives. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, andtreatment facilities in Atlanta, Chicago and Phoenix. City of Hope’s affiliated group of organizations includesTranslational Genomics Research InstituteandAccessHopeTM. For more information about City of Hope, follow us onFacebook,Twitter,YouTube,InstagramandLinkedIn.

City of Hope’s commitment to Diversity, Equity, and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds, and experiences to our work -- and that our teams align with the people we serve in order to build trust and understanding. We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds, and perspectives; this is reflected in our work and represented in our people.

Position Summary

The department of pathology of the City of Hope Medical Center is recruiting a postdoctoral fellow to work with a group of researchers in the joint laboratory of Dr. Binghui Shen and Dr. Christina Wei.

The candidate is expected to be an innovative scientist with knowledge and experience in molecular oncology (integrative multiomic data analysis), precision pathology (advanced Assisted image analysis on immunofluorescence-stained slides), Immunohistochemical assays and genomic profiling. Interests and knowledge in the analysis of data generated through next generation sequencing and other global technologies including transcriptomic and mutational analysis as well as correlative analysis of different datasets would be desirable. Our group works very collaboratively in a supportive and stimulatory environment with the goal of understanding the pathogenesis of DNA damage response, discovering novel therapeutic targets, and improving the treatment and outcome of women's cancer patients.

The Shen/Wei laboratory has been focusing on DNA replication/repair pathway components, cancer genetics and epigenetics, and cancer etiological and therapeutics modeling. The laboratory is seeking Ph.D. graduates or equivalents in the field of biological/medical sciences with ambition for a scientific career and interest in DNA replication and repair, genome stability, cancer biology and skills in molecular biology, genetics or biochemistry are encouraged to apply. Bioinformatics and data mining skills are a plus for considerations.

Basic education, experience and skills required for consideration:

·A Ph.D. degree in life or biology, genomics/genetics or a related discipline is required.

·Experience using Next-Generation sequencing analysis and gene editing in lab investigation.

·Proficient in molecular biological techniques including transfection, transduction, cloning, vector construction, reporter assay and western blot.

·Ability and interest in developing new assays as needed.

·Basic proficiency in programming desirable.

·Values research integrity, careful experimental work, and collaborative research.

Preferred education, experience, and skills for consideration:

·Training background in molecular/cellular biology, biochemistry or genetics.

·Ambition and interest in DNA repair and cancer biology.

Additional Information:

·For more information on Dr. Binghui Shen’s research please visithere.

·The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate’s experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.

·As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

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