丹麥哥本哈根大學2024年招聘博士后職位（心臟功能基因組學）

哥本哈根大學 （英文: University of Copenhagen; 丹麥文: Københavns Universitet；簡稱：UCPH / KU）坐落于丹麥王國首都哥本哈根，是丹麥最高學府，4EU＋聯盟、國際研究型大學聯盟、歐洲研究型大學聯盟、歐洲首都大學聯盟、歐洲大學協會成員。大學建于1479年，已有500多年歷史，從最初只對社會名流開放，現已發展成一所學科全面、集教育與科研于一身的世界研究型大學。

2-year postdoc fellowship in the group of Cardiac Functional Genomics

Copenhagen University

Denmark

February 08, 2024

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Contract Type:fixed-term position

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Department of Biomedical Sciences Faculty of Health and Medical Sciences University of Copenhagen Denmark

The group of Functional Genomics at the University of Copenhagen is looking for a highly motivated postdoc to work on atrial development, morphogenesis and function using the zebrafish model organism.

Our group and research The newly started group of Functional Genomics is headed by assistant professor Pia Rengtved Lundegaard. We have a keen interest in the structure and function of the atrium, and to study this we use the zebrafish as a model organism. We study all aspects of development, morphogenesis and function of the heart, with a particular interest in the atrium.

Lundegaard group website

Project description

Atrial function has been underappreciated in its role in the proper function of ventricles. We have previously shown that mutations in genes associated with dilated cardiomyopathy are also associated with atrial fibrillation and atrial cardiomyopathy (Ahlberg et al. Nature Comms. 2018, Collins et al, PNAS 2019, Vad et al, JACC: Basic to Transnational Science, 2023).

Thus, we have a keen interest in the development and function of the atrium in health and disease. We are particularly interested in studying how mutations in cytoskeletal genes of the cardiomyocyte influence the development and the function of the atrium, and how atrial dysfunction affects the structure and the function of the ventricle. The postdoc recruited for this project will work on existing mutants available in the lab, as well as generate new mutant and transgenic zebrafish models. The techniques used to study the potential phenotypes will include both imaging techniques and electrophysiology, using the zebrafish as a model organism. Furthermore, the project will include CRISPR-Cas9 genome editing, RNA sequencing (bulk and single cell), molecular biology methods, such as cloning and PCR, protein analysis and high-resolution imaging using confocal microscopy. Basic computer skills and an interest in bioinformatics (R-studio or Python) is an advantage as well.

Postdoctoral advisor is Assistant professor Pia Rengtved Lundegaard , Functional Genomics group , Department of Biomedical Sciences, plundegaard@sund.ku.dk.

Start: 1st of May 2024

Duration: 2 years

Job description Your key tasks as a postdoc at SUND are:

· Carry through an independent research project under supervision.

· Teaching of undergraduate students and disseminate your knowledge.

· Supervise PhD and MSc students.

· Write scientific papers.

· Write grant applications.

Mandatory skills needed for the position

· Curious mind-set and high work ethics

· Prior experience with zebrafish as a model organism

· An animal experimental course (FELASA B or C) is mandatory for applying for the position.

· Fluent in English (written and spoken)

Place of employment

The place of employment is at the Lundegaard Group, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and a zebrafish facility.

Terms of employment The average weekly working hours are 37 hours per week.

The position is a fixed-term position limited to a period of 2 years. The starting date is 1st May 2024.

Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 36,400 DKK/approx. 4,880 EUR (October 2023 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the Job Structure for Academic Staff at Universities 2020.

Questions For specific information about the postdoc position please contact assistant professor Pia R. Lundegaard, plundegaard@sund.ku.dk.

Application procedure Your application must be submitted electronically by clicking ‘Apply now' below. The application must include the following documents in PDF format:

1. Motivated letter of application (max. one page)

2. CV incl. education, experience, language skills and other skills relevant for the position

3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.

4. Publication list (if applicable)

5. The names of two referees.

Application deadline: 8th February2024, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.

Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at https: // employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held 3 weeks after application deadline.

The Faculty of Health and Medical Sciences comprises approximately 7500 students, 1500 PhD students and 3200 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community. The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.

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