一、中心簡介
首都醫學科學創新中心（簡稱創新中心）是北京市新成立的具有獨立法人資格的新型研發機構。創新中心以推動醫學科學發展、改善人類健康為目標，開展生物醫學研究，致力于提升醫學科學創新與成果轉化能力，提高疾病診斷和治療水平。我們將匯聚世界高水平科學家，與首都醫學教育和科學研究優質資源緊密合作，打造多學科交叉融合的科研平臺，綜合自由探索、醫學目標導向、有組織科研等途徑，實踐新型科研模式和體制機制，逐步推進醫教研產的深度融合，培養適應醫學科學創新發展的優秀人才。
二、實驗室介紹
柴國梁，本科和碩士畢業于清華大學，比利時魯汶大學生物醫學與制藥科學博士，美國加州大學圣地亞哥分校博士后。目前為首都醫學科學創新中心研究員，首都醫科大學
三、實驗室研究方向
實驗室致力于研究神經系統疑難罕見病與常見疾病的遺傳因素及其致病機理，并開發創新靶向干預治療策略。主要研究課題:
1.神經系統疑難罕見病與復雜疾病的遺傳學及致病機制研究；
2.探索神經系統疾病中的中樞和外周免疫紊亂及炎癥調控機制；
3.開發針對神經系統疾病的治療新方法與新策略。
四、實驗室代表文章
NEJM. 2021. 385:1292-301
Neuron. 2021. 109, 241-256
Brain. 2022. 24;145(4):1551-1563
J Neuroinflammation. 2023. 20(1):63
JAMA Neurology. 2025. 82(3):247-257
五、崗位信息
01、科研助理
科研助理應具有扎實的分子生物學、神經生物學、實驗動物學、基礎醫學等相關專業背景，熟練掌握與動物相關的實驗室技術。有動物飼養，立體定位注射相關經驗者優先。
1）崗位職責
本崗位招聘1名科研助理，主要負責實驗室小鼠飼養工作，基因型鑒定，表型評估，立體定位注射以支持實驗室在動物方面的科學研究。
2）任職要求
1.大學本科學歷及以上，分子生物學、神經生物學、實驗動物學、神經病學、遺傳學、免疫學、基礎醫學等相關專業；
2.有動物實驗經驗，熟練掌握小鼠基因鑒定、表型評估、立體定位注射等技術；
3.具備較強的學習能力及動手能力，能迅速上手掌握新技術；
4.具備良好的溝通能力和團隊協作能力。
六、福利待遇
1.根據應聘者的工作經驗和能力，提供具有市場競爭力的薪酬（詳情面談）；
2.享受五險一金、帶薪年假、體檢和補充醫療保險等；
3.支持個人發展，提供必要的工作相關專業培訓。
七、申請方法
請將以下材料合并為一個PDF文件，發送至：guoliang.chai@cimrbj.ac.cn
1.簡歷，含聯系方式；
2.研究興趣和經驗簡介。
聯系人：
聯系地址：北京市豐臺區右安門外西頭條10號-首都醫學科學創新中心
本招聘長期有效，至招聘到合適人選為止。
ABOUT CIMR
Chinese Institutes for Medical Research (CIMR) is a newly founded institution dedicated to fundamental and translational medical research. The CIMR is located at the main campus of the
Laboratory Introduction
Guoliang Chai holds a Ph.D. in Biomedical and Pharmaceutical Sciences from UC Louvain, Belgium, and completed his postdoctoral training at the
Laboratory Research Directions
Dr. Chai’s laboratory is dedicated to investigating the genetic factors and pathogenic mechanisms underlying rare and common neurological diseases, with the goal of developing innovative targeted therapeutic strategies. The projects of the lab includes:
a. Genetics and Pathogenic Mechanisms of rare/complex neurological disorders;
b. Central and Peripheral Immune Dysregulation in neurological diseases;
c. Novel Therapeutic Approaches for neurological disorders.
Representative Publications
NEJM. 2021. 385:1292-301
Neuron. 2021. 109, 241-256
Brain. 2022 24;145(4):1551-1563
J Neuroinflammation. 2023. 20(1):63
JAMA Neurology. 2025. 82(3):247-257
Open Positions
Molecular Biology Technician
The candidate should possess a solid academic background in molecular biology, neurobiology, laboratory animal science, or related disciplines, with proficient skills in animal-related laboratory techniques. Prior experience in animal husbandry and stereotaxic injection techniques will be considered advantageous.
Main Responsibilities
We are seeking a highly motivated Research Assistant to join our team. The successful candidate will be primarily responsible for:
Routine care and management of laboratory mice
Genotyping and phenotypic characterization
Performing stereotaxic injections to support in vivo research
This position plays a critical role in supporting the laboratory's animal-based scientific investigations.
Qualifications
a. Education: Bachelor's degree or higher in molecular biology, neurobiology, laboratory animal science, neurology, genetics, immunology, basic medicine, or related fields.
b. Technical Skills:
Prior experience with animal experiments.
Proficiency in mouse genotyping, phenotypic characterization, and stereotactic injection techniques.
c. Abilities:Strong learning capacity and hands-on skills, with the ability to quickly master new techniques.
d. Excellent communication and teamwork skills.
Welfare Treatment
a. Competitive salary based on the applicant’s work experience and ability (salary negotiable).
b. Social insurance and housing fund, supplementary medical insurance, physical examination and paid annual leave.
c. Opportunities for career development and available professional guidance.
How to apply
Please email the following documents as a single PDF to: guoliang.chai@cimrbj.ac.cn:
a. Updated CV with contact information
b. Short summary of research experience & interests
Contact Person: Dr. Chai
Address: No.10 Xitoutiao, Youanmenwai, Fengtai District,
This recruitment will remain open until suitable candidates are selected.
為防止簡歷投遞丟失請抄送一份至：boshijob@126.com（郵件標題格式：應聘職位名稱+姓名+學歷+專業+中國博士人才網）
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