美國希望之城2023年招聘博士后職位（心血管生物學與腫瘤學）

希望之城國家醫療中心(City of Hope NationalMedical Center)是一所頂尖的美國非盈利研究和治療中心，專注于癌癥、糖尿病和其他危及生命的疾病。

Postdoctoral Fellow - Cardiovascular Biology and Oncology

City of Hope

Job Description

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. June-Wha Rhee in City of Hope’s Department of Medicine, Division of Cardiology.

The lab’s research focuses on understanding the biology underlying cancer therapy-induced cardiovascular complications by leveraging human-induced pluripotent stem cells (iPSCs) as well as patient samples, genomics and leading-edge computational biology.

There has been remarkable progress in cancer treatments resulting in improved long-term survival. However, cardiovascular complications related to these therapies can cause treatment interruptions and lead to worse oncologic and cardiovascular outcomes. Therefore, there is a critical need to better understand 1) why and through what mechanisms the cancer therapy-related cardiotoxicity occurs, 2) who is at risk and 3) how to mitigate or prevent this toxicity. Our lab is working toward addressing these questions so that cancer patients can safely be treated with life-saving cancer therapies. Specifically, we believe metabolism and biologic aging are critical in modulating this risk and are working to define their roles by leveraging genome editing technology, multi-omics and advanced bioinformatics utilizing patient-specific iPSCs and patient samples.

The goal of the Rhee Lab is to pioneer basic and translational research in cardio-oncology so that we can find a way to protect our cancer patients from any cardiovascular complications. For this, we will employ cutting-edge technologies, bioinformatics, and patient-specific stem cells.

The candidate will investigate molecular mechanisms of cancer therapy-induced cardiotoxicity, leveraging cutting-edge computational biology, genome editing technologies, and induced pluripotent stem cell models.

Basic education, experience and skills required for consideration:

·PhD or M.D. in molecular biology, genetics, biochemistry, cell biology, bioinformatics or related field

·Previous experience in iPSC and/or mouse models, cardiovascular biology, molecular biology, genetics, or bioinformatics is highly desired but not required.

Additional Information:

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

Contact email:

jrhee@coh.org

Salary / Pay Rate Information:

Pay Rate: $30.00 - $33.13 / hour

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