加拿大渥太華大學2024年招聘博士后職位（癌癥表觀遺傳學和藥物發現）

渥太華大學（University of Ottawa, 法語: Université d'Ottawa），簡稱渥大、uOttawa或UofO，始建于1848年，位于加拿大首都渥太華。渥太華大學是加拿大頂級研究型大學，加拿大最古老、全球規模最大的英法雙語大學，G7國家U7頂級大學聯盟成員，加拿大U15研究型大學聯盟成員，英聯邦大學協會成員；其前身是無玷圣母獻主會在1848年創辦的Bytown學院，1866年獲得由維多利亞女王頒發的皇家特許狀（Royal Charter ，加拿大僅有9所大學擁有），1965年重組出渥太華大學和圣保羅大學。

Postdoctoral Fellow in Cancer Epigenetics and Drug Discovery

University of Ottawa

Job Description

The Benoit lab at the University of Ottawa has a Postdoctoral Fellow position available to study human colorectal cancer and develop future therapeutic strategies to target cancer stem cells. The overarching goal of the Benoit lab is to develop new anticancer agents targeting essential elements of human colon cancer stem cell chromatin organization. The research led by the candidate will utilize patient-derived tissues, high-content imaging, organoid-based 3D bioprinting systems, high-throughput drug screening, genome-editing tools, and in vivo tumorigenesis models to evaluate the impact of small molecules on epigenetic regulation mechanisms essential to neoplastic stemness. The candidate will also work with bulk, spatial, and single-cell genomic analyses, spectral flow cytometry, and single-cell proteomics.

This position offers a unique opportunity for professional growth and development in a collaborative and dynamic research environment. We offer competitive salary and benefits package, with the possibility to renew/extend based on performance.‍

Published research work by the Benoit lab is found here:

https://pubmed.ncbi.nlm.nih.gov/?term=Benoit%20YD%20Ottawa&sort=date

Qualifications:

The position is for a PhD or MD/PhD holder, who graduated from a highly recognized academic program.

A strong background in cancer and/or stem cell biology is required. Advanced skills in cellular imaging, molecular biology, flow cytometry, mammalian cell culture, in vivo models, and genomic data analysis are highly desirable. Priority will be given to candidates with demonstrated computational biology knowledge and proficiency (Proficiency in data analysis using R or Python).

Ability to work independently, show self-initiative and attention to detail, and motivation to explore new techniques and concepts are essential.

Publication of relevant research work in recognized scientific journals is an asset.

Outstanding written and oral communication skills, team spirit, and adherence to highest ethical principles when collecting experimental data and working with laboratory animals are necessary.

Candidates can expect a positive, competitive, and success-oriented work environment, tailored to their personal career and publications goals. The successful candidate will engage in vibrant scientific discourse with the University of Ottawa molecular sciences and stem cell biologist community. Regular meetings with the PI will assure mutual expectations are met.

Only shortlisted candidates will be contacted.

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