University of Turku

We are looking for a creative postdoc level researcher interested in myeloid cell biology to the laboratory of Alexander Mildner for a fixed-term position. The successful applicant is expected to begin their work in mid 2022, but starting date is negotiable. The duration of the position will be until the end of 2024 with the possibility for an extension.

We investigate the development and function of monocytes and macrophages during homeostasis and pathologies, such as experimental autoimmune encephalomyelitis (EAE), Alzheimer’s disease and atherosclerosis. Our aim is the identification of transcription factors that are involved in the epigenetic regulation of myeloid differentiation or contribute to their pathogenic functions. We will use FACS sorting, transgenic mouse models, single cell RNA-sequencing and other epigenetic profiling techniques (e.g. ATAC-seq, ChIP-seq) to investigate the contribution of specific cell populations to disease development. We will also anticipate close collaborations with clinicians in order to intensify ex vivo research on human cells. For further information about the research scope and research papers, please visit: https://www.researchgate.net/profile/Alexander-Mildner-2

We invite qualified, motivated, and especially critical thinking scientists of any nationality to apply for this position. Please visit also https://inflames.utu.fi/vacancies/ for other positions available in InFLAMES Research Flagship and Dr. Mildner’s group.

Research Environment

The position will be seated in the laboratory of Dr. Alexander Mildner at MediCity Research Laboratory. University of Turku. The project is funded by the InFLAMES Research Flagship. The InFLAMES Flagship is a joint effort of University of Turku, ÅboAkademi University and the associated ecosystem. It aims at being an internationally recognized, top-level, immunological research and development cluster attracting both researchers and business partners.

Requirements

The successful candidate should hold a PhD in medicine, biology, life sciences or other relevant discipline and solid experience in molecular biology and immunology. A strong background in mouse experiments is essential, as well as a strong experience in state-of-the-art cell and molecular profiling technologies such as FACS, RNA-seq, ATAC-seq or ChIP-seq. Experience in CRISPR/Cas9 and background in innate immune cells are valued. Strong interpersonal skills, including written and oral communication in English are essential. Skills in bioinformatics (e.g. NGS data analysis, R/Phyton, linux) and interest in science-related activities outside of the lab (science slam, open discussions etc.) are of advantage.

The qualification requirements of the position are available on the University of Turku Rules of Procedure.

Salary

The salary offered is determined in accordance with the University salary system for teaching and research personnel, and it is at levels 5-6 on the job demands chart, where the task specific salary component is 3000,49 – 3498,98 € per month. In addition a personal work performance component will be paid. The personal performance component is 6% – 50% of the task-specific base salary.

A six (6) month trial period applies to the positions.

What to do next

Applications must be submitted on 29 April 2022 at the latest (23.59.59 Finnish time) via the University of Turku electronic application form at www.utu.fi/careers. The link to the electronic application form is located at the beginning of the announcement (Apply for the job).

In your application, please include

•a personal statement or motivation letter containing a description of your scientific background and research interests, and how they possibly relate to the research of the Mildner lab at the InFLAMES Flagship (max. 2 pages)

•a CV

•degree certificates

•a list of publications with citation count

For further information about the position, please contact Dr. Alexander Mildner, alexander.mildner@utu.fi

Regarding the recruitment process, please contact HR Specialist KristiinaNuutila, kristiina.nuutila@utu.fi, Tel. +358 503135224

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