深圳灣實驗室簡介
深圳灣實驗室(生命信息與生物醫藥廣東省實驗室)是廣東省、深圳市建設粵港澳國際科技創新中心和綜合性國家科學中心的重大戰略部署,是深圳建設中國特色社會主義先行示范區行動中,全力支持的重大創新載體。
深圳灣實驗室面向世界科技前沿和人民生命健康,緊緊圍繞國家戰略布局,以協同攻克生命健康重大科學難題為導向,以腫瘤、代謝與心血管、神經退行性、傳染性等重大疾病的預防、診斷和治療為焦點,以IT+BT融合及多學科交叉為特色,開展疾病機理、生命信息、創新藥物、醫學成像等領域研究。在深圳灣實驗室,重大疾病問題與前沿學科技術互為經緯,以科研單元矩陣式設計打破傳統學科界限,充分促進學科交叉優勢;以自由探索與協同攻關雙輪驅動,散點偵察與陣地突破的結合,對生命健康問題開展更全面且更精準的研究,實踐新型舉國體制科研新模式。
實驗室致力于營造高效的創新體系與蓬勃的創新生態,打造高精尖技術支撐平臺,推動創新要素高效配置的轉化研究范式,激發各類人才的創造性。實驗室聚集生命科學優勢力量,聯合建設粵港澳大灣區協同創新共同體,努力成為國際一流的科技創新高地。
研究所/中心簡介
醫藥健康技術與工程研究所,面向健康中國國家戰略需求,聚焦制約我國醫藥健康產業發展的"卡脖子"科學和技術難題,延攬國際優勢科研和頂尖人才,通過多學科交叉和跨界融合,構建醫藥健康創新研究與應用轉化的平臺和基地,開展引領國際醫藥健康領域的高水平研究,在創新藥物、新型疫苗、健康干預等方面實現系列原創性科學技術突破,開展產學研醫全鏈條創新轉化研究,形成原始創新能力和集成創新能力,培養高端人才,助力企業完成醫藥健康工業技術改造和轉型升級,支撐一批具有國際競爭力和行業引領力的醫藥與健康科技企業,不斷提升深圳醫藥與健康產業的國際競爭力。
課題組簡介
課題組組長介紹:孫勇奎院士,醫藥健康技術與工程研究所召集人之一,美國國家工程院院士,原力生命科學有限公司的創始人之一。1977年,恢復高考那年,孫院士考入廈門大學,并獲得學士及碩士學位;在美國加州理工學院,取得博士學位。畢業后,孫院士在默克、默沙東連續工作二十余載,擁有非常豐富的藥物研發經驗,曾兩次獲得美國綠色化學總統獎。其在默沙東工作期間創立的默沙東催化實驗室,至今仍是世界上最具有影響力的催化實驗室之一。目前,由他創辦的公司融資金額已超過10億元。
課題組研究方向:抗腫瘤新藥研發,包括尋找靶點、合成催化、臨床評價等。
招聘崗位
崗位一:助理研究員
需求人數:1人
崗位工作內容:
The candidate will lead a research group team to identify or validate novel targets, and investigate the mechanism of drug resistance. The successful candidate will be expected to propose research directions and drug discovery projects with global first-in-class or best-in-class potentials. He or She will independently design, execute and manage internal research projects, collaborate with other groups within the institute and manage external collaborations. In addition, the candidate will be able to communicate research updates in the form of oral presentations internally and/or externally and deliver results in written documents for patent filings and publications.
Successful candidate will work closely with two academician PI’s (Prof. Peter Lobie and Prof. Yongkui Sun), and has opportunity to work closely with scientists in a bio-tech company for translational research.
Responsibilities:
1.Build a research group team to explore cutting-edge scientific topics on Disease/ translational biology. It’s preferred to have rich research experience in the field of immuno-oncology and targeted therapy.
2.Identify and validate novel drug targets and new mechanisms of actions, and propose early drug discovery projects with high potentials.
3. Work independently to conduct research related to cancer therapy and define tumor intrinsic resistance mechanisms of immune-checkpoint or target therapy.
4. Independently lead a scientific team and collaborate with other research scientists from the institute and manage external collaborations to deliver results for high value patent or high impact factor publication.
崗位要求:
1. PhD in Cancer Biology, Immunology, Pharmacology or other related Biological sciences. Research experiences in Cancer cell biology, cell cycle/signaling, drug resistance or related field are highly desirable.
2. With postdoctoral working experience in world renowned lab, industry experience preferred.
3. Familiar with drug discovery, and experience to lead drug discovery programs from hit generation to IND-enabling studies would be advantageous.
4. Good tracking record of scientific publications.
條件待遇:
1. 薪資待遇:稅前年薪不低于40萬,具體薪酬可再議;
2. 基本保障:按照深圳市繳費比例上限繳納五險一金,享受帶薪年休假(12天起/年)、節日慰問等福利;
3. 特色福利:員工體檢、免費班車、節假日慰問、員工活動等;
4. 科研環境:提供國際水準的研究條件,包括良好的工作環境、充足的研究經費、精良的實驗儀器和積極主動的工作氛圍;
5. 人才補貼:實驗室全力協助申請市級人才引進補貼,包括博士學歷首次來深工作的可申報一次性生活補貼10萬元,博后出站首次來/留深工作可申報獎勵30萬元等;
6. 職位晉升:科研業績優秀,并具有獨立研發精神的研究員可競聘“啟航學者”職位,可獲得獨立科研經費,進行自主招聘和申報市級人才獎勵等;
7. 生活關懷:按照深圳市及實驗室規定,協助辦理落戶、申請公租房(勤誠達、鳳凰英薈城、安居鳴鹿苑、紅坳村等項目),以及協調子女入園/學等事宜。
崗位二:博士后(生物方向/化學方向)
需求人數:5人
生物方向崗位工作內容:
1. Help to design experiments.
2. Conduct experiments, analyse data.
3. Write papers and grants proposals.
4. Mentor students, and compete for fellowships.
崗位要求:
1. PhD in cancer biology or related area, the doctoral degree obtained within 3 years.
2. Be under the age of 35 and physically adequate.
3.Expertise in DNA and protein biology (including work on oncogene proteins and transcription factors) is preferred.
4.Strong background and working knowledge of basic molecular and cellular biology techniques such as cell culture, cloning, real-time PCR and western blotting.
5. Any experience with animal modeling, analyses of human clinical samples, is highly desirable.
6. Experience in drug development, mechanisms and interactions.
7.A proven track record in the form of publications in international English language journals
8. Ability to communicate in written and spoken English.
化學方向崗位工作內容:
1.Help to design experiments.
2.Conduct experiments, analyse data.
3. Write papers and grants proposals.
4.Mentor students, and compete for fellowships.
崗位要求:
1. Ph.D. degree in organic chemistry, organometallic chemistry, catalysis, bio-catalysis or other related education background. Strong research experience in late-stage functionalization, high-throughput experimentation, enzyme catalysis and photochemical catalysis is preferred.
2. Candidates who have experiences in drug discovery and development are highly preferred, including but not limited to drug synthetic route design, computational chemistry for designing of biological active molecules.
3.Self motivator, capability in carrying out independent research work and with good publish track record in the related fields.
4. With enthusiasm for scientific research; Strong interpersonal & communication skills, English stills a plus.
條件待遇:
1. Besides competitive compensation, postdoc can obtain application-based living subsidies of 180,000 RMB per year provided by Shenzhen government.
2.Qualified postdoc can also obtain 100,000 RMB per year according to Fenji Postdoctoral Program of SZBL.
3.After leaving SZBL, postdocs can apply for research grants of 300,000 RMB in total for three years if they continue to conduct scientific research in Shenzhen and when the related application requirements are met. Also, qualified postdocs are encouraged to apply for Shenzhen Bay Fellow to receive corresponding benefits based on specific application requirements.
4.When the postdoc program ends, postdocs who decide to stay in SZBL can obtain application-based living subsidies of 300,000 RMB provided by Guangming District.
崗位三:研究助理
需求人數:3人
崗位工作內容:
1.協助博士后及助理研究員開展日常科研工作,并能夠按照計劃獨立完成交辦的實驗。
2. 根據項目需要,及時、準確、完整、科學地記錄實驗結果,參與數據審核,問題分析和實驗結果統計歸納。
3. 能夠進行文獻檢索及相關報告的撰寫,及時了解跟蹤行業熱點,能夠主動學習新知識新技術。
崗位要求:
1. 生物醫學類相關專業背景的碩士學歷。
2.熟悉基本的分子細胞生物學及免疫學的實驗技能,有相關從業經驗者優先。
3.具備較強的學習能力和科研思維,能夠獨立分析和解決問題;責任心強,有較好的溝通能力。
4. 有一定的英語閱讀能力,具備英語六級或以上水平者優先。
5.能夠長期穩定工作者優先。
條件待遇:
1.薪資待遇:稅前12-15萬/年,視個人情況可再議;
2. 基本保障:按照深圳市繳費比例上限繳納五險一金,享受國家法定節假日、帶薪年休假(6天或12天以上/年)等假期;
3. 特色福利:員工年度健康體檢、補充醫療保險、免費班車、員工活動、節日慰問等;
4. 科研環境:提供國際水準的研究條件和工作環境,包括充足的研究經費,尖端的技術支撐平臺,跨國界的人才資源等;
5.人才激勵:根據本人意愿和工作情況,課題組可以推薦申請人到香港高校繼續深造,攻讀博士學位;
6. 生活關懷:按照深圳市及實驗室規定,協助辦理落戶、申請公租房(勤誠達、光僑雅苑、鳳凰英薈城、安居鳴鹿苑、紅坳)等事宜。
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